To prevent migrain pain, take Fioricet with food or milk. Pain medications work best in preventing pain before it occurs. Once the pain becomes intense, the medication is not as effective in relieving it. Take Fioricet as prescribed. Do not increase your dose of Fioricet or take it more frequently without your doctor's approval.To prevent migrain pain, take Fioricet with food or milk. Pain medications work best in preventing pain before it occurs. Once the pain becomes intense, the medication is not as effective in relieving it. Take Fioricet as prescribed. Do not increase your dose of Fioricet or take it more frequently without your doctor's approval.To prevent migrain pain, take Fioricet with food or milk. Pain medications work best in preventing pain before it occurs. Once the pain becomes intense, the medication is not as effective in relieving it. Take Fioricet as prescribed. Do not increase your dose of Fioricet or take it more frequently without your doctor's approval.To prevent migrain pain, take Fioricet with food or milk. Pain medications work best in preventing pain before it occurs. Once the pain becomes intense, the medication is not as effective in relieving it. Take Fioricet as prescribed. Do not increase your dose of Fioricet or take it more frequently without your doctor's approval.